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. 2015 Oct 8:11:255.
doi: 10.1186/s12917-015-0567-6.

Heterogeneity in the prevalence and intensity of bovine trypanosomiasis in the districts of Amuru and Nwoya, Northern Uganda

Harriet Angwech  1 , Jack H P Nyeko  2 , Elizabeth A Opiyo  3 , Joseph Okello-Onen  4 , Robert Opiro  5 , Richard Echodu  6 , Geoffrey M Malinga  7   8 , Moses N Njahira  9 , Robert A Skilton  10
Affiliations

Heterogeneity in the prevalence and intensity of bovine trypanosomiasis in the districts of Amuru and Nwoya, Northern Uganda

Harriet Angwech et al. BMC Vet Res. .

Abstract

Background: Livestock trypanosomiasis, transmitted mainly by tsetse flies of the genus Glossina is a major constraint to livestock health and productivity in the sub-Saharan Africa. Knowledge of the prevalence and intensity of trypanosomiasis is important in understanding the epidemiology of the disease. The objectives of this study were to (a) assess the prevalence and intensity of trypanosome infections in cattle, and (b) to investigate the reasons for the heterogeneity of the disease in the tsetse infested districts of Amuru and Nwoya, northern Uganda.

Methods: A cross-sectional study was conducted from September, 2011 to January, 2012. Blood samples were collected from 816 cattle following jugular vein puncture, and screened for trypanosomes by HCT and ITS-PCR. A Pearson chi-squared test and logistic regression analyses were performed to determine the association between location, age, sex, and prevalence of trypanosome infections.

Results: Out of the 816 blood samples examined, 178 (22 %) and 338 (41 %) tested positive for trypanosomiasis by HCT and ITS-PCR, respectively. Trypanosoma vivax infection accounted for 77 % of infections detected by ITS-PCR, T. congolense (16 %), T. brucei s.l (4 %) and mixed (T. vivax/ T. congolense/T.brucei) infections (3 %). The risk of trypanosome infection was significantly associated with cattle age (χ (2) = 220.4, df = 3, P < 0.001). The highest proportions of infected animals were adult males (26.7 %) and the least infected were the less than one year old calves (2.0 %). In addition, the risk of trypanosome infection was significantly associated with sex (χ (2) = 16.64, df = 1, P < 0.001), and males had a significantly higher prevalence of infections (26.8 %) than females (14.6 %).

Conclusion: Our results indicate that the prevalence and intensity of trypanosome infections are highly heterogeneous being associated with cattle age, location and sex.

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Figures

Fig. 1
Fig. 1
Location of study sites in Amuru and Nwoya districts, northern Uganda (Sampled parishes and bleeding centers). All parishes in Nwoya district included in the study border Murchison Falls National Park (i.e. they are found in the wildlife-livestock interface). Amuru’s parishes on the other hand are located in an area where the density of game animals is low and therefore, livestock constitute the main source of tsetse blood meal
Fig. 2
Fig. 2
The prevalence of bovine trypanosomiasis in the nine parishes of Amuru and Nwoya districts, northern Uganda
See this image and copyright information in PMC

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