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Review
. 2015:216:189-213.
doi: 10.1007/978-3-319-15856-3_10.

Implantation and Establishment of Pregnancy in Human and Nonhuman Primates

Ren-Wei Su  1 , Asgerally T Fazleabas  2
Affiliations
Review

Implantation and Establishment of Pregnancy in Human and Nonhuman Primates

Ren-Wei Su et al. Adv Anat Embryol Cell Biol. 2015.

Abstract

Implantation and the establishment of pregnancy are critical for the propagation of the species, but yet remain the limiting steps in human and primate reproduction. Successful implantation requires a competent blastocyst and a receptive endometrium during a specific window of time during the menstrual cycle to initiate the bilateral communication required for the establishment of a successful pregnancy. This chapter provides an overview of these processes and discusses the molecular mechanisms associated with implantation of the blastocyst and decidualization of the uterus in primates.

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Figures

Fig. 10.1
Fig. 10.1
Endometrial responses to the embryonic signal in primates. Epithelial and stromal cells respond to chorionic gonadotropin (CG) and interleukin 1 β (IL-1β) during the establishment of pregnancy in the primates. Inserts A and B reflect the changes in epithelial and stromal cell responses which are described in detail in expanded form in Panels (a) and (b)
See this image and copyright information in PMC

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