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. 2015 Nov;16(11):1421-6.
doi: 10.15252/embr.201541337. Epub 2015 Oct 8.

No time to waste--the ethical challenges created by CRISPR: CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism, raises many ethical and regulatory issues beyond the use to manipulate human germ line cells

Arthur L Caplan  1 , Brendan Parent  1 , Michael Shen  2 , Carolyn Plunkett  3
Affiliations

No time to waste--the ethical challenges created by CRISPR: CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism, raises many ethical and regulatory issues beyond the use to manipulate human germ line cells

Arthur L Caplan et al. EMBO Rep. 2015 Nov.
No abstract available

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Figures

Figure 1
Figure 1. Gene drives can be used to alter population-wide traits
A gene drive is preferentially inherited by all offspring and would quickly spread itself in the target population. The endonuclease cuts the homologous wild-type chromosome; repairing the break using homologous recombination therefore copies the gene drive onto the wild-type chromosome. Gene-drive technology could be used to eradicate diseases, such as malaria or dengue fever, by targeting wild populations of disease-transmitting mosquitoes but could have unanticipated secondary effects on other species. Figure adapted from .
See this image and copyright information in PMC

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References

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