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Comment
. 2015 Oct 8;126(15):1734-5.
doi: 10.1182/blood-2015-08-665067.

ALL and osteonecrosis

Paul S Gaynon  1
Affiliations
Free article
Comment

ALL and osteonecrosis

Paul S Gaynon. Blood. .
Free article

Abstract

In this issue of Blood, Karol et al establish a link between glutamate receptor polymorphisms and osteonecrosis, using a large discovery cohort and 2 validation cohorts. One validation cohort included patients under treatment of acute lymphoblastic leukemia (ALL) and the second is patients receiving glucocorticoid treatment of various other indications.

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  • Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.
    Karol SE, Yang W, Van Driest SL, Chang TY, Kaste S, Bowton E, Basford M, Bastarache L, Roden DM, Denny JC, Larsen E, Winick N, Carroll WL, Cheng C, Pei D, Fernandez CA, Liu C, Smith C, Loh ML, Raetz EA, Hunger SP, Scheet P, Jeha S, Pui CH, Evans WE, Devidas M, Mattano LA Jr, Relling MV. Karol SE, et al. Blood. 2015 Oct 8;126(15):1770-6. doi: 10.1182/blood-2015-05-643601. Epub 2015 Aug 11. Blood. 2015. PMID: 26265699 Free PMC article.

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