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Case Reports
. 2015 Oct 9:2015:bcr2015212128.
doi: 10.1136/bcr-2015-212128.

Successful medical treatment of infective endocarditis caused by Candida parapsilosis in an immunocompromised patient

Hans Alexi Reyes  1 , Walter Hernan Carbajal  1 , Luis Manuel Valdez  2 , Claudia Lozada  3
Affiliations
Case Reports

Successful medical treatment of infective endocarditis caused by Candida parapsilosis in an immunocompromised patient

Hans Alexi Reyes et al. BMJ Case Rep. .

Abstract

Candida spp is a common pathogen of nosocomial infections that has increased in recent decades, with mortality rates close to 40% in cases of systemic candidiasis. One type of presentation is infective endocarditis, which, by its prolonged need for treatment, represents a constant challenge for clinicians. We describe a 36-year-old woman, recently diagnosed with ovarian cancer, who developed aortic valve infective endocarditis caused by Candida parapsilosis and who was treated with oral antifungal medication, with no surgical intervention required.

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Figures

Figure 1
Figure 1
A two-dimensional transthoracic echocardiogram showing a mobile, pediculated echodense 5×8 mm image adjacent to the aortic valve.
Figure 2
Figure 2
Repeat transthoracic echocardiogram showing no vegetation in the aortic valve.
See this image and copyright information in PMC

References

    1. Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev 2007;20:133–63. 10.1128/CMR.00029-06 - DOI - PMC - PubMed
    1. Sifuentes-Osornio J, Corzo-León DE, Ponce-de-León LA. Epidemiology of Invasive Fungal Infections in Latin America. Curr Fungal Infect Rep 2012;6:23–34. 10.1007/s12281-011-0081-7 - DOI - PMC - PubMed
    1. Pappas PG, Kauffman CA, Andes D et al. . Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009;48:503–35. 10.1086/596757 - DOI - PMC - PubMed
    1. Nishimura RA, Otto CM, Bonow RO et al. , American College of Cardiology; American College of Cardiology/American Heart Association; American Heart Association. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg 2014;148:e1–132. 10.1016/j.jtcvs.2014.05.014 - DOI - PubMed
    1. Almirante B, Rodríguez D, Cuenca-Estrella M et al. . Epidemiology, risk factors, and prognosis of Candida parapsilosis bloodstream infections: case-control population-based surveillance study of patients in Barcelona, Spain, from 2002 to 2003. J Clin Microbiol 2006;44:1681–5. 10.1128/JCM.44.5.1681-1685.2006 - DOI - PMC - PubMed

Publication types

Supplementary concepts