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. 2015;43(1):15-26.
doi: 10.1097/ASA.0000000000000033.

Long-term Functional Outcomes after Regional Anesthesia: A Summary of the Published Evidence and a Recent Cochrane Review

Arthur Atchabahian  1 , Michael Andreae  2
Affiliations

Long-term Functional Outcomes after Regional Anesthesia: A Summary of the Published Evidence and a Recent Cochrane Review

Arthur Atchabahian et al. Refresh Courses Anesthesiol. 2015.
No abstract available

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Figures

Figure 1
Figure 1
Normal perception: Panel A shows the normal pain pathways; the peripheral primary nociceptor transmits a pain signal to the secondary neuron in the spinal dorsal horn. From there, the pain is transmitted to the brain. Central sensitization: In Panel B, the intense barrage of pain signals from a surgical incision leads to permanent signal amplification in the spinal horn. This is the pathophysiological basis for hyperalgesia and persistent pain after surgery. Prevention of chronic pain: In Panel C, regional anesthesia prevents the development of chronic pain after surgery by blocking the pain signal. No central sensitization occurs.
Figure 2
Figure 2
Forest plot comparison of regional analgesia vs. conventional analgesia for dichotomous pain outcomes at six months for thoracotomy and breast cancer surgery. (From Andreae MH, Andreae DA. Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery. Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD007105. DOI: 10.1002/14651858.CD007105.pub2. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.)
See this image and copyright information in PMC

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