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Clinical Trial
. 1989 Feb;148(5):465-7.
doi: 10.1007/BF00595916.

Combined therapy of enuresis alarm and desmopressin in the treatment of nocturnal enuresis

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Clinical Trial

Combined therapy of enuresis alarm and desmopressin in the treatment of nocturnal enuresis

R N Sukhai et al. Eur J Pediatr. 1989 Feb.

Abstract

Twenty-eight children with primary nocturnal enuresis were blindly allocated at random to a combination of enuresis alarm and 20 micrograms intranasal desmopressin or alarm and placebo for 2 weeks. Patients received the other therapy after a 2-week treatment-free period. The combined treatment of desmopressin and alarm showed 5.1 +/- 0.4 (mean +/- SEM) dry nights per week and resulted in significantly more dry nights per week during the 2 weeks of observation than placebo and alarm (4.1 +/- 0.4, P less than 0.05).

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