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. 2015 Oct 13:15:85.
doi: 10.1186/s12874-015-0079-x.

Classification and prevalence of spin in abstracts of non-randomized studies evaluating an intervention

Clément Lazarus  1   2   3 , Romana Haneef  4   5 , Philippe Ravaud  6   7   8   9   10 , Isabelle Boutron  11   12   13   14
Affiliations

Classification and prevalence of spin in abstracts of non-randomized studies evaluating an intervention

Clément Lazarus et al. BMC Med Res Methodol. .

Abstract

Background: Spin represents specific reporting strategies, either intentional or unintentional, to convince the reader that the beneficial effect of the experimental intervention in terms of efficacy and safety is greater than that shown by the results. The objectives of this study were to 1) develop a classification of spin specific to non-randomized studies assessing an intervention and 2) estimate the prevalence of spin in abstracts of reports of such studies.

Methods: In a first step, we developed a specific classification of spin for non-randomized studies by a literature review and pilot study. In a second step, 2 researchers trained in the field of methodology evaluated the prevalence of spin in the abstract of all non-randomized studies assessing an intervention published in the BioMed Central Medical Series journals between January 1, 2011 and December 31, 2013. All disagreements were resolved by consensus. We also determined whether the level of spin in abstract conclusions was high (spin reported without uncertainty or recommendations for further trials), moderate (spin reported with some uncertainty or recommendations for further trials) or low (spin reported with uncertainty and recommendations for further trials).

Results: Among the 128 assessed articles assessed, 107 (84%) had at least one example of spin in their abstract. The most prevalent strategy of spin was the use of causal language, identified in 68 (53%) abstracts. Other frequent strategies were linguistic spin, inadequate implications for clinical practice, and lack of focus on harm, identified in 33 (26%), 25 (20%), and 34 (27%) abstracts respectively. Abstract conclusions of 61 (48%) articles featured a high level of spin.

Conclusion: Abstract of reports of non-randomized studies assessing an intervention frequently includes spin. Efforts to reduce the prevalence of spin in abstract for such studies are needed.

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Figures

Fig. 1
Fig. 1
Flowchart for the selection and inclusion of articles from the BioMed Central Medical Series Journals assessing therapeutic interventions through non-randomized designs and reasons for exclusion
See this image and copyright information in PMC

References

    1. Horton R. The rhetoric of research. BMJ. 1995;310(6985):985–987. doi: 10.1136/bmj.310.6985.985. - DOI - PMC - PubMed
    1. Fletcher RH, Black B. “Spin” in scientific writing: scientific mischief and legal jeopardy. Med Law. 2007;26(3):511–525. - PubMed
    1. Boutron I, Dutton S, Ravaud P, Altman DG. Reporting and interpretation of randomized controlled trials with statistically nonsignificant results for primary outcomes. JAMA. 2010;303(20):2058–2064. doi: 10.1001/jama.2010.651. - DOI - PubMed
    1. Ochodo EA, De Haan MC, Reitsma JB, Hooft L, Bossuyt PM, Leeflang MM. Overinterpretation and misreporting of diagnostic accuracy studies: evidence of “spin”. Radiology. 2013;267(2):581–588. doi: 10.1148/radiol.12120527. - DOI - PubMed
    1. Vera-Badillo FE, Shapiro R, Ocana A, Amir E, Tannock IF. Bias in reporting of end points of efficacy and toxicity in randomized, clinical trials for women with breast cancer. Ann Oncol. 2013;24(5):1238–1244. doi: 10.1093/annonc/mds636. - DOI - PubMed

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