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. 2016 Jul;20(6):1347-54.
doi: 10.1007/s00784-015-1622-1. Epub 2015 Oct 13.

The association between hypodontia and dental development

Brunilda Dhamo  1   2 , Strahinja Vucic  1   2 , Mette A R Kuijpers  3 , Vincent W V Jaddoe  2   4 , Albert Hofman  2   4 , Eppo B Wolvius  1   2 , Edwin M Ongkosuwito  5   6   7
Affiliations

The association between hypodontia and dental development

Brunilda Dhamo et al. Clin Oral Investig. 2016 Jul.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] J Orthod. 2017 Mar;44(1):74. doi: 10.1080/14653125.2016.1275610. Epub 2017 Jan 12. J Orthod. 2017. PMID: 28079474 No abstract available.

Abstract

Objectives: In this cross-sectional study, we aimed to investigate the pattern of hypodontia in the Dutch population and determine the association between hypodontia and dental development in children with and without hypodontia, applying three different standards, Dutch, French Canadian, and Belgian, to estimate dental age.

Methods: We used dental panoramic radiographs (DPRs) of 1488 children (773 boys and 715 girls), with a mean age of 9.76 years (SD = 0.24) participating in a population-based cohort study in Rotterdam, the Netherlands, born in 2002-2004, and 452 children (219 boys and 233 girls) with a mean age of 9.83 years (SD = 1.09) participating in a mixed-longitudinal, interdisciplinary population-based cohort study in Nijmegen, the Netherlands born in 1960-1968.

Results: The prevalence of hypodontia in the Generation R Study was 5.6 % (N = 84) and 5.1 % (N = 23) in the Nijmegen Growth Study. Linear regression analysis showed that children with hypodontia had a 0.37 [95 % CI (-0.53,-0.21)] to 0.52 [95 % CI (-0.76,-0.38)] years lower dental age than children without hypodontia. The ordinal regression analysis showed a delay in development of mandibular second premolars [1.68 years; 95 %CI (-1.90,-1.46)], mandibular first premolars [0.57 years; 95 % CI (-0.94,-0.20)], and mandibular second molars [0.47 years; 95 % CI (-0.84,-0.11)].

Conclusion: These findings suggest that children with hypodontia have a delayed dental development.

Clinical relevance: The delay of dental development in children with hypodontia should be taken into consideration and therefore orthodontists should recognize that a later start of treatment in these patients may be necessary.

Keywords: Dental age; Dutch dental age standards; Teeth development; Tooth agenesis.

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Figures

Fig. 1
Fig. 1
Dental age of study population assessed from Dutch, French-Canadian, and Belgian standards are presented as a function of chronological age of children
Fig. 2
Fig. 2
Association of hypodontia with stages of dental development for each of the seven left mandibular teeth, expressed by estimates of b-coefficients and 95 % confidence intervals; assessed from ordinal regression model using developmental stage (A/1, B/2, C/3, D/4, E/5, F/6, G/7, H/8) as a dependent variable and hypodontia status (No-ref., Yes) as a determinant in Model 1. Model 2 was additionally adjusted for age, gender, and study population. Model 3 was adjusted for variables used in previous model and additionally for ethnicity and maternal age at birth of a child
Fig. 3
Fig. 3
The forest plot of studies on the association between hypodontia and dental development
See this image and copyright information in PMC

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