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. 2015 Nov;44(8):1195-210.
doi: 10.1097/MPA.0000000000000500.

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium

Elham Afghani  1 , Stephen J Pandol, Tooru Shimosegawa, Robert Sutton, Bechien U Wu, Santhi Swaroop Vege, Fred Gorelick, Morihisa Hirota, John Windsor, Simon K Lo, Martin L Freeman, Markus M Lerch, Yoshihisa Tsuji, Gil Y Melmed, Wahid Wassef, Julia Mayerle
Affiliations

Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium

Elham Afghani et al. Pancreas. 2015 Nov.

Abstract

An international symposium entitled "Acute pancreatitis: progress and challenges" was held on November 5, 2014 at the Hapuna Beach Hotel, Big Island, Hawaii, as part of the 45th Anniversary Meeting of the American Pancreatic Association and the Japanese Pancreas Society. The course was organized and directed by Drs. Stephen Pandol, Tooru Shimosegawa, Robert Sutton, Bechien Wu, and Santhi Swaroop Vege. The symposium objectives were to: (1) highlight current issues in management of acute pancreatitis, (2) discuss promising treatments, (3) consider development of quality indicators and improved measures of disease activity, and (4) present a framework for international collaboration for development of new therapies. This article represents a compilation and adaptation of brief summaries prepared by speakers at the symposium with the purpose of broadly disseminating information and initiatives.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Figure demonstrating the gut lymph theory.
FIGURE 2
FIGURE 2
Perfusion CT 12 hours after the onset of severe pancreatitis. Perfusion CT can detect pancreatic and peripancreatic ischemia. A, On a contrast enhanced CT, the pancreas appears homogenously enhanced. B, Perfusion CT shows slower blood flow in the pancreas (arrows) as seen by the lack of perfusion.
FIGURE 3
FIGURE 3
Progression of acute pancreatitis and potential treatment targets.
FIGURE 4
FIGURE 4
Demonstration of how CRAI works in improving the clinical outcome in severe acute pancreatitis. PAMPs, pathogen-associated molecular patterns.
FIGURE 5
FIGURE 5
An integrated approach to the development of new medicines depends on the whole cycle of translation.
FIGURE 6
FIGURE 6
Acute pancreatitis activity index: pre-Delphi.
See this image and copyright information in PMC

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