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. 2016 Apr;71(4):380-2.
doi: 10.1136/thoraxjnl-2015-207496. Epub 2015 Oct 14.

MesobanK UK: an international mesothelioma bioresource

Robert C Rintoul  1 , Doris M Rassl  2 , Jacki Gittins  3 , Stefan J Marciniak  4 ; MesobanK collaborators
Collaborators, Affiliations

MesobanK UK: an international mesothelioma bioresource

Robert C Rintoul et al. Thorax. 2016 Apr.

Abstract

Malignant pleural mesothelioma causes the greatest societal burden of all the asbestos-related diseases. Progress in better understanding tumour biology will be facilitated by the availability of quality-assured annotated tissue. MesobanK has been created to establish a bioresource of pleural mesothelioma tissue linked to detailed anonymised clinical data. When complete, the bioresource will comprise a 750-patient tissue microarray and prospectively collected tissue, blood and pleural fluid from 300 patients with mesothelioma. Twenty-six new cell lines have also been developed. MesobanK meets all appropriate ethical and regulatory procedures and has recently opened to requests for tissue and data.

Keywords: Asbestos Induced Lung Disease; Histology/Cytology; Mesothelioma; Pleural Disease.

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Figures

Figure 1
Figure 1
Flow diagram for patient samples and data. QC, quality control.
See this image and copyright information in PMC

References

    1. Health and Safety Executive. http://www.hse.gov.uk/statistics/causdis/mesothelioma/index.htm
    1. WHO. Elimination of asbestos-related diseases. http://whqlibdoc.who.int/hq/2006/WHO_SDE_OEH_06.03_eng.pdf
    1. National Cancer Research Institute. A Review of Research in Mesothelioma and Other Asbestos Related Diseases. November 2010. http://lunguk.org/OneStopCMS/Core/CrawlerResourceServer.aspx?resource=eb...
    1. National Cancer Research Institute. Confederation of Cancer Biobanks: Human Research Tissue Banks/Resources/Biobanks Guiding Principles. November 2006. http://www.oncoreuk.org/pages/documents/HumanResearchTissueBanksGuidingP...
    1. Medical Research Council (MRC) Operational and Ethical Guidelines on Human Tissue and Biological Materials for Use in Research. http://www.mrc.ac.uk/pdf-tissue_guide_fin.pdf

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