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Review
. 2016:1333:17-28.
doi: 10.1007/978-1-4939-2854-5_2.

Persisters: Methods for Isolation and Identifying Contributing Factors--A Review

Sarah E Rowe  1 , Brian P Conlon  1 , Iris Keren  1 , Kim Lewis  2
Affiliations
Review

Persisters: Methods for Isolation and Identifying Contributing Factors--A Review

Sarah E Rowe et al. Methods Mol Biol. 2016.

Abstract

Persister cells are phenotypic variants surviving a lethal dose of antibiotic, sufficient to kill the bulk of an exponential phase population. In this chapter we summarize current techniques to isolate persisters and discuss limitations associated with identifying mechanisms of persister formation.

Keywords: Antibiotic; Biofilm; Hip mutant; Toxin-antitoxin (TA) modules.

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