Continuing Challenges for the Clinical Laboratory for Detection of Carbapenem-Resistant Enterobacteriaceae
- PMID: 26468504
- PMCID: PMC4652095
- DOI: 10.1128/JCM.02668-15
Continuing Challenges for the Clinical Laboratory for Detection of Carbapenem-Resistant Enterobacteriaceae
Erratum in
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Correction for Humphries and McKinnell, Continuing Challenges for the Clinical Laboratory for Detection of Carbapenem-Resistant Enterobacteriaceae.J Clin Microbiol. 2016 Feb;54(2):509. doi: 10.1128/JCM.03175-15. J Clin Microbiol. 2016. PMID: 26822773 Free PMC article. No abstract available.
Abstract
Detecting carbapenem-resistant Enterobacteriaceae (CRE) can be difficult. In particular, the absence of FDA-cleared automated antimicrobial susceptibility test (AST) devices that use revised Clinical and Laboratory Standards Institute (CLSI) carbapenem breakpoints for Enterobacteriaceae and the lack of active surveillance tests hamper the clinical laboratory. In this issue of the Journal of Clinical Microbiology, Lau and colleagues (A. F. Lau, G. A. Fahle, M. A. Kemp, A. N. Jassem, J. P. Dekker, and K. M. Frank, J Clin Microbiol 53:3729-3737, 2015, http://dx.doi.org/10.1128/JCM.01921-15) evaluate the performance of a research-use-only PCR for the detection of CRE in rectal surveillance specimens.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Comment on
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Clinical Performance of Check-Direct CPE, a Multiplex PCR for Direct Detection of bla(KPC), bla(NDM) and/or bla(VIM), and bla(OXA)-48 from Perirectal Swabs.J Clin Microbiol. 2015 Dec;53(12):3729-37. doi: 10.1128/JCM.01921-15. Epub 2015 Sep 2. J Clin Microbiol. 2015. PMID: 26338860 Free PMC article.
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References
-
- Centers for Disease Control and Prevention. 2013. Antibiotic resistance threats in the United States, 2013. Centers for Disease Control and Prevention, Atlanta, GA. http://www.cdc.gov/drugresistance/threat-report-2013/ Accessed 10 October 2015.
-
- Sievert DM, Ricks P, Edwards JR, Schneider A, Patel J, Srinivasan A, Kallen A, Limbago B, Fridkin S; National Healthcare Safety Network (NHSN) Team and Participating NHSN Facilities. 2013. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009–2010. Infect Control Hosp Epidemiol 34:1–14. doi:10.1086/668770. - DOI - PubMed
-
- Lin MY, Lyles-Banks RD, Lolans K, Hines DW, Spear JB, Petrak R, Trick WE, Weinstein RA, Hayden MK; Centers for Disease Control and Prevention Epicenters Program. 2013. The importance of long-term acute care hospitals in the regional epidemiology of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae. Clin Infect Dis 57:1246–1252. doi:10.1093/cid/cit500. - DOI - PMC - PubMed
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