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. 1989;104(1-2):63-75.
doi: 10.1007/BF01313808.

A bio-engineered rubella E1 antigen

G M Terry  1 , L Ho-Terry, P Londesborough, K R Rees
Affiliations

A bio-engineered rubella E1 antigen

G M Terry et al. Arch Virol. 1989.

Abstract

The major rubella envelope protein, E1, and a segment of it, comprising amino acids 207-353, have been separately expressed as fusion proteins with the IgG binding region of Staphylococcus aureus protein A in Escherichia coli. The proteins carry E1-specific antigenicity recognized by monoclonal antibodies raised against whole virus confirming that correct glycosylation is not required for antigenicity. The use of these bioengineered antigens in immunoassays for diagnosis of rubella infection and for immunization in experimental animals is described.

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References

    1. J Med Virol. 1986 Jun;19(2):111-22 - PubMed
    1. Methods Enzymol. 1986;121:848-55 - PubMed
    1. J Biol Chem. 1984 Feb 10;259(3):1695-702 - PubMed
    1. J Mol Biol. 1983 Jun 5;166(4):557-80 - PubMed
    1. J Immunol. 1970 Apr;104(4):826-34 - PubMed

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