Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1989 Mar:80:17-23.
doi: 10.1289/ehp.898017.

Coupling growth arrest and adipocyte differentiation

G Ailhaud  1 , C Dani, E Z Amri, P Djian, C Vannier, A Doglio, C Forest, D Gaillard, R Négrel, P Grimaldi
Affiliations
Review

Coupling growth arrest and adipocyte differentiation

G Ailhaud et al. Environ Health Perspect. 1989 Mar.

Abstract

The complete differentiation program of preadipose cells can be divided into early and late events. The expression of early markers takes place at growth arrest (G1/S boundary), whereas that of late markers, leading to terminal differentiation, takes place after a limited number of mitoses of early marker-containing cells. Only terminal differentiation requires the presence of growth hormone and triiodothyronine and results in the formation of triacylglycerol-filled, nondividing cells. The events of adipose cell differentiation which take place in vitro allow a better understanding of the development of adipose tissue in vivo.

PubMed Disclaimer

References

    1. Exp Cell Res. 1984 Jun;152(2):368-77 - PubMed
    1. J Biol Chem. 1983 Aug 25;258(16):10083-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1984 Sep;81(17):5440-4 - PubMed
    1. Exp Cell Res. 1985 Feb;156(2):513-27 - PubMed
    1. J Biol Chem. 1985 Apr 10;260(7):4424-31 - PubMed

LinkOut - more resources