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. 2015 Oct 16:16:305.
doi: 10.1186/s12891-015-0737-5.

Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study

Shigeyuki Muraki  1 , Toru Akune  2 , Masatoshi Teraguchi  3 , Ryohei Kagotani  4 , Yoshiki Asai  5 , Munehito Yoshida  6 , Fumiaki Tokimura  7 , Sakae Tanaka  8 , Hiroyuki Oka  9 , Hiroshi Kawaguchi  10 , Kozo Nakamura  11 , Noriko Yoshimura  12
Affiliations

Quadriceps muscle strength, radiographic knee osteoarthritis and knee pain: the ROAD study

Shigeyuki Muraki et al. BMC Musculoskelet Disord. .

Abstract

Background: The objective of this study was to clarify the association of quadriceps muscle strength with knee pain using a large-scale, population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study.

Methods: From the 2566 subjects at the third visit of the ROAD study, the present study analyzed 2152 subjects who completed radiographic examinations and measurements of muscle strength and mass (690 men and 1462 women; mean age, 71.6 ± 12.2 years). Knee pain was assessed by an experienced orthopedist. Knee osteoarthritis (OA) was defined according to Kellgren-Lawrence (KL) grade. Quadriceps muscle strength and muscle mass at the lower limbs were measured by the Quadriceps Training Machine (QTM-05F, Alcare Co., Ltd. Tokyo, Japan) and the Body Composition Analyzer MC-190 (Tanita Corp., Tokyo, Japan), respectively.

Results: Quadriceps muscle strength and weight bearing index (WBI: quadriceps muscle strength by weight) were significantly associated with knee pain after adjustment for age and body mass index, whereas grip strength and muscle mass at the lower limbs were not. The significant association of quadriceps muscle strength with knee pain was independent of radiographic knee OA.

Conclusion: The present cross-sectional study showed an independent association of quadriceps muscle strength with knee pain.

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Figures

Fig. 1
Fig. 1
Prevalence of knee pain by Kellgren-Lawrence (KL) grade. The number of subjects in each KL grade is shown in parentheses
Fig. 2
Fig. 2
Prevalence of knee pain by muscle strength at the lower limb in men and women. The number of subjects in each muscle strength is shown in parentheses
Fig. 3
Fig. 3
Prevalence of knee pain by weight bearing index in men and women. The number of subjects in each muscle strength is shown in parentheses. Weight bearing index was calculated as quadiceps muscle strength/weight
See this image and copyright information in PMC

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