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Review
. 2016 Aug;92(Pt A):90-101.
doi: 10.1016/j.nbd.2015.10.012. Epub 2015 Oct 23.

Controversies in preterm brain injury

Anna A Penn  1 , Pierre Gressens  2 , Bobbi Fleiss  2 , Stephen A Back  3 , Vittorio Gallo  4
Affiliations
Review

Controversies in preterm brain injury

Anna A Penn et al. Neurobiol Dis. 2016 Aug.

Abstract

In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

Keywords: Brain development; Neuroimaging; Preterm brain injury; White matter injury.

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