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. 2015 Summer;7(3):1871.

Tumor-Induced Osteomalacia

Rajiv Kumar  1 , Andrew L Folpe  2 , Brian P Mullan  3
Affiliations

Tumor-Induced Osteomalacia

Rajiv Kumar et al. Transl Endocrinol Metab. 2015 Summer.
No abstract available

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Figures

Figure 1
Figure 1
Figure 1A. Skeletal radiograph of the patient with nutritional osteomalacia. Note the presence of pseudofractures of the metatarsals (arrows). Figure 1B. Technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan of patient with osteomalacia. Note uptake over the ribs and sacro-iliac region.
Figure 1
Figure 1
Figure 1A. Skeletal radiograph of the patient with nutritional osteomalacia. Note the presence of pseudofractures of the metatarsals (arrows). Figure 1B. Technetium-99m methylene diphosphonate (Tc-99m MDP) bone scan of patient with osteomalacia. Note uptake over the ribs and sacro-iliac region.
Figure 2
Figure 2
Photomicrograph of bone (Goldner’s stain) showing normal bone (top left panel) and osteomalacic bone (top right panel) and normal mineralization (bottom left panel) and a mineralization defect (bottom right panel) after the administration of tetracycline labels.
Figure 3
Figure 3
Low power photomicrograph (10x) of a phosphaturic mesenchymal tumor, showing the characteristic admixture of bland spindled cells, small blood vessels, adipocytes and calcified matrix. High power photomicrograph (40x:) of a phosphaturic mesenchymal tumor, with an osteoclastic reaction to the distinctive calcified matrix produced by the lesional cells.
Figure 4
Figure 4
Figure 4A. Magnetic resonance scan of a patient with TIO. The arrow points to the tumor. Figure 4B. Technetium 99m sestamibi scans of a patient with TIO (same patient as in figure 4B). Arrow and arrow head point to tumor.
Figure 4
Figure 4
Figure 4A. Magnetic resonance scan of a patient with TIO. The arrow points to the tumor. Figure 4B. Technetium 99m sestamibi scans of a patient with TIO (same patient as in figure 4B). Arrow and arrow head point to tumor.
Figure 5
Figure 5
Phosphorus homeostasis in humans.
Figure 6
Figure 6
Adaptations to changes in dietary phosphate intake.
Figure 7
Figure 7
Mechanisms of hypophosphatemia in TIO and the inherited rickets
See this image and copyright information in PMC

References

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