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. 2015 Oct;13(10):1191-202.
doi: 10.6004/jnccn.2015.0148.

Central Nervous System Cancers, Version 1.2015

Louis Burt Nabors  1 , Jana Portnow  1 , Mario Ammirati  1 , Joachim Baehring  1 , Henry Brem  1 , Paul Brown  1 , Nicholas Butowski  1 , Marc C Chamberlain  1 , Robert A Fenstermaker  1 , Allan Friedman  1 , Mark R Gilbert  1 , Jona Hattangadi-Gluth  1 , Matthias Holdhoff  1 , Larry Junck  1 , Thomas Kaley  1 , Ronald Lawson  1 , Jay S Loeffler  1 , Mary P Lovely  1 , Paul L Moots  1 , Maciej M Mrugala  1 , Herbert B Newton  1 , Ian Parney  1 , Jeffrey J Raizer  1 , Lawrence Recht  1 , Nicole Shonka  1 , Dennis C Shrieve  1 , Allen K Sills Jr  1 , Lode J Swinnen  1 , David Tran  1 , Nam Tran  1 , Frank D Vrionis  1 , Stephanie Weiss  1 , Patrick Yung Wen  1 , Nicole McMillian  1 , Anita M Engh  1
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Central Nervous System Cancers, Version 1.2015

Louis Burt Nabors et al. J Natl Compr Canc Netw. 2015 Oct.

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS cancers. Primary and metastatic brain tumors are a heterogeneous group of neoplasms with varied outcomes and management strategies. These NCCN Guidelines Insights summarize the NCCN CNS Cancers Panel's discussion and highlight notable changes in the 2015 update. This article outlines the data and provides insight into panel decisions regarding adjuvant radiation and chemotherapy treatment options for high-risk newly diagnosed low-grade gliomas and glioblastomas. Additionally, it describes the panel's assessment of new data and the ongoing debate regarding the use of alternating electric field therapy for high-grade gliomas.

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