Metabolic plasticity of central carbon metabolism protects mycobacteria
- PMID: 26483480
- PMCID: PMC4629367
- DOI: 10.1073/pnas.1518171112
Metabolic plasticity of central carbon metabolism protects mycobacteria
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Comment on
-
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5834-43. doi: 10.1073/pnas.1510932112. Epub 2015 Oct 1. Proc Natl Acad Sci U S A. 2015. PMID: 26430237 Free PMC article.
Similar articles
-
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5834-43. doi: 10.1073/pnas.1510932112. Epub 2015 Oct 1. Proc Natl Acad Sci U S A. 2015. PMID: 26430237 Free PMC article.
-
Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism.Chem Biol. 2011 Aug 26;18(8):1011-20. doi: 10.1016/j.chembiol.2011.06.004. Chem Biol. 2011. PMID: 21867916
-
Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons.J Neurosci Res. 2006 Feb 15;83(3):450-8. doi: 10.1002/jnr.20749. J Neurosci Res. 2006. PMID: 16416424
-
Oxidative metabolism.Ann N Y Acad Sci. 2000;924:164-9. doi: 10.1111/j.1749-6632.2000.tb05575.x. Ann N Y Acad Sci. 2000. PMID: 11193793 Review.
-
The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration.Mol Neurobiol. 2005;31(1-3):43-63. doi: 10.1385/MN:31:1-3:043. Mol Neurobiol. 2005. PMID: 15953811 Review.
Cited by
-
CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs.Front Cell Infect Microbiol. 2018 Nov 6;8:385. doi: 10.3389/fcimb.2018.00385. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30460206 Free PMC article.
-
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions.BMC Syst Biol. 2018 Mar 2;12(1):25. doi: 10.1186/s12918-018-0557-y. BMC Syst Biol. 2018. PMID: 29499714 Free PMC article.
-
Proteome Profiling of Mycobacterium tuberculosis Cells Exposed to Nitrosative Stress.ACS Omega. 2022 Jan 14;7(4):3470-3482. doi: 10.1021/acsomega.1c05923. eCollection 2022 Feb 1. ACS Omega. 2022. PMID: 35128256 Free PMC article.
-
Lactobacilli Isolated From Wild Boar (Sus scrofa) Antagonize Mycobacterium bovis Bacille Calmette-Guerin (BCG) in a Species-Dependent Manner.Front Microbiol. 2019 Jul 30;10:1663. doi: 10.3389/fmicb.2019.01663. eCollection 2019. Front Microbiol. 2019. PMID: 31417502 Free PMC article.
-
Feedback between environment and traits under selection in a seasonal environment: consequences for experimental evolution.Proc Biol Sci. 2018 Apr 11;285(1876):20180284. doi: 10.1098/rspb.2018.0284. Proc Biol Sci. 2018. PMID: 29643216 Free PMC article.
References
-
- Bunik VI, Fernie AR. Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: A cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation. Biochem J. 2009;422(3):405–421. - PubMed
-
- Guest JR. The Leeuwenhoek Lecture, 1995. Adaptation to life without oxygen. Philos Trans R Soc Lond B Biol Sci. 1995;350(1332):189–202. - PubMed
-
- Pitson SM, Mendz GL, Srinivasan S, Hazell SL. The tricarboxylic acid cycle of Helicobacter pylori. Eur J Biochem. 1999;260(1):258–267. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources