Pancreatic cancer: Classifying pancreatic cancer using gene expression profiling
- PMID: 26484444
- PMCID: PMC5013537
- DOI: 10.1038/nrgastro.2015.180
Pancreatic cancer: Classifying pancreatic cancer using gene expression profiling
Abstract
Despite some advances in our understanding of the molecular characteristics of pancreatic cancer, much more progress is needed. In a new study, RNA profiling of pancreatic cancers was used to identify gene signatures of tumour cells and stromal cells to help predict patient outcomes.
Comment on
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Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.Nat Genet. 2015 Oct;47(10):1168-78. doi: 10.1038/ng.3398. Epub 2015 Sep 7. Nat Genet. 2015. PMID: 26343385 Free PMC article.
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- Moffitt RA, et al. Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma. Nat. Genet. http://dx.doi.org/10.1038/ng.3398. - DOI - PMC - PubMed
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- Infante JR, et al. Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma. J. Clin. Oncol. 2007;25:319–325. - PubMed
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