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. 2015 Sep 1;3(3):203-208.
doi: 10.1089/big.2015.0016.

Real-Time Assessment of Wellness and Disease in Daily Life

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Real-Time Assessment of Wellness and Disease in Daily Life

Dennis Ausiello et al. Big Data. .

Abstract

The next frontier in medicine involves better quantifying human traits, known as "phenotypes." Biological markers have been directly associated with disease risks, but poor measurement of behaviors such as diet and exercise limits our understanding of preventive measures. By joining together an uncommonly wide range of disciplines and expertise, the Kavli HUMAN Project will advance measurement of behavioral phenotypes, as well as environmental factors that impact behavior. By following the same individuals over time, KHP will liberate new understanding of dynamic links between behavioral phenotypes, disease, and the broader environment. As KHP advances understanding of the bio-behavioral complex, it will seed new approaches to the diagnosis, prevention, and treatment of human disease.

Keywords: big data analytics; big data architecture; big data industry standards.

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References

    1. Welter D, MacArthur J, Morales J, et al. . The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 2014;42:D1001–D1006 - PMC - PubMed
    1. Karlsson F, Tremaroli V, Nielsen J, Backhed F. Assessing the human gut microbiota in metabolic diseases. Diabetes. 2013;62:3341–3349 - PMC - PubMed
    1. Karlsson FH, Fak F, Nookaew I, et al. . Symptomatic atherosclerosis is associated with an altered gut metagenome. Nat Commun. 2012;3:1245. - PMC - PubMed
    1. Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: Human gut microbes associated with obesity. Nature. 2006;444:1022–1023 - PubMed
    1. Karlsson FH, Tremaroli V, Nookaew I, et al. . Gut metagenome in European women with normal, impaired and diabetic glucose control. Nature. 2013;498:99–103 - PubMed

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