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Case Reports
. 2015 Oct;19(4):364-6.
doi: 10.1055/s-0035-1547522. Epub 2015 Mar 13.

Foreign Body in Jugal Mucosa

Affiliations
Case Reports

Foreign Body in Jugal Mucosa

Thiago Luís Infanger Serrano et al. Int Arch Otorhinolaryngol. 2015 Oct.

Abstract

Introduction Foreign body in the oral cavity may be asymptomatic for long time and only sometimes it can lead to a typical granulomatous foreign body reaction. Some patients may complain of oral pain and present signs of inflammation with purulent discharge. A granuloma is a distinct, compact microscopic structure composed of epithelioid-shaped macrophages typically surrounded by a rim of lymphocytes and filled with fibroblasts and collagen. Nowadays, the increase of cosmetic invasive procedures such as injection of prosthetic materials in lips and cheeks may lead to unusual forms of inflammatory granulomas. Objectives Describe an unusual presentation of a foreign body reaction in the buccal mucosa due to previous injection of cosmetic agent. Resumed Report A 74-year-old woman was referred to the Department of Otorhinolaryngology, Head and Neck Surgery to investigate the presence of multiple painless, bilateral nodules in the buccal mucosa, with progressive growth observed during the previous 2 months. The histologic results showed a foreign body inflammatory reaction. Conclusion Oral granulomatosis lesions represent a challenging diagnosis for clinicians and a biopsy may be necessary. Patients may feel ashamed to report previous aesthetic procedures, and the clinicians must have a proactive approach.

Keywords: differential diagnoses; esthetic surgery; foreign body reaction; granulomatosis; orofacial.

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Figures

Fig. 1
Fig. 1
Biopsy showing the yellowish coloration and hard consistency from right buccal mucosa.
Fig. 2
Fig. 2
Histopathologic view (hematoxylin and eosin 10 × ) showing epithelioid-shaped macrophages surrounded by a rim of lymphocytes (full arrows), filled with fibroblasts and collagen (arrow with ball head).
Fig. 3
Fig. 3
Histopathologic view (hematoxylin and eosin 40 × ): multinucleated giant cells with haphazardly/peripherally nuclei shape (arrows), associated with areas without substance, indicating foreign body particles (*).

References

    1. Puliyel D, Balouch A, Ram S, Sedghizadeh P P. Foreign body in the oral cavity mimicking a benign connective tissue tumor. Case Rep Dent. 2013;2013:369510. - PMC - PubMed
    1. Jham B C, Nikitakis N G, Scheper M A, Papadimitriou J C, Levy B A, Rivera H. Granulomatous foreign-body reaction involving oral and perioral tissues after injection of biomaterials: a series of 7 cases and review of the literature. J Oral Maxillofac Surg. 2009;67(2):280–285. - PubMed
    1. Manthey D E, Storrow A B, Milbourn J M, Wagner B J. Ultrasound versus radiography in the detection of softtissue foreign bodies. Ann Emerg Med. 1996;28(1):7–9. - PubMed
    1. Alawi F. Granulomatous diseases of the oral tissues: differential diagnosis and update. Dent Clin North Am. 2005;49(1):203–221, x. - PubMed
    1. Silveira V AS, de Carmo E D, Colombo C ED, Cavalcante A SR, Carvalho Y R. Intraosseous foreign-body granuloma in the mandible subsequent to a 20-year-old work-related accident. Med Oral Patol Oral Cir Bucal. 2008;13(10):E657–E660. - PubMed

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