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. 2016 Mar 1;71(3):e79-82.
doi: 10.1097/QAI.0000000000000873.

Reduced Baseline Sensitivity to Maraviroc Inhibition Among R5 HIV-1 Isolates From Individuals With Severe Immunodeficiency

Ulf Karlsson  1 , Johanna Repits, Liselotte Antonsson, Erik Cederfjäll, Bengt Ljungberg, Martin Ålenius, Alan Sabirsh, Magnus Gisslen, Joakim Esbjörnsson, Marianne Jansson
Affiliations

Reduced Baseline Sensitivity to Maraviroc Inhibition Among R5 HIV-1 Isolates From Individuals With Severe Immunodeficiency

Ulf Karlsson et al. J Acquir Immune Defic Syndr. .

Abstract

Supplemental Digital Content is Available in the Text.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
R5 HIV-1 AIDS isolates display reduced baseline sensitivity to MVC inhibition. A, CD4+ T-cell counts correlate with R5 virus baseline sensitivity to MVC inhibition (r = −0.64, P = 0.007). B, Non-AIDS R5 isolates were more sensitive to inhibition by MVC (lower IC90) than patients with R5 HIV-1 AIDS (P = 0.004). Figures display 1 representative experiment of 3 performed.
See this image and copyright information in PMC

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