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Review
. 2015:2015:615681.
doi: 10.1155/2015/615681. Epub 2015 Oct 1.

Sleep Deficiency and Deprivation Leading to Cardiovascular Disease

Michelle Kohansieh  1 , Amgad N Makaryus  2
Affiliations
Review

Sleep Deficiency and Deprivation Leading to Cardiovascular Disease

Michelle Kohansieh et al. Int J Hypertens. 2015.

Abstract

Sleep plays a vital role in an individual's mental, emotional, and physiological well-being. Not only does sleep deficiency lead to neurological and psychological disorders, but also the literature has explored the adverse effects of sleep deficiency on the cardiovascular system. Decreased quantity and quality of sleep have been linked to cardiovascular disease (CVD) risk factors, such as hypertension, obesity, diabetes, and dyslipidemia. We explore the literature correlating primary sleep deficiency and deprivation as a cause for cardiovascular disease and cite endothelial dysfunction as a common underlying mechanism.

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References

    1. Palagini L., Bruno R. M., Gemignani A., Baglioni C., Ghiadoni L., Riemann D. Sleep loss and hypertension: a systematic review. Current Pharmaceutical Design. 2013;19(13):2409–2419. doi: 10.2174/1381612811319130009. - DOI - PubMed
    1. Knutson K. L., Spiegel K., Penev P., Van Cauter E. The metabolic consequences of sleep deprivation. Sleep Medicine Reviews. 2007;11(3):163–178. doi: 10.1016/j.smrv.2007.01.002. - DOI - PMC - PubMed
    1. Karlsson B., Knutsson A., Lindahl B. Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people. Occupational and Environmental Medicine. 2001;58(11):747–752. doi: 10.1136/oem.58.11.747. - DOI - PMC - PubMed
    1. Cappuccio F. P., Cooper D., Delia L., Strazzullo P., Miller M. A. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. European Heart Journal. 2011;32(12):1484–1492. doi: 10.1093/eurheartj/ehr007. - DOI - PubMed
    1. National Sleep Foundation. 2013 Executive Summary; National Bedroom Poll. 2013, http://sleepfoundation.org/sites/default/files/RPT495a.pdf.

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