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Case Reports
. 2015 Oct;94(42):e1722.
doi: 10.1097/MD.0000000000001722.

Heterotopic Gastric Mucosa in the Distal Part of Esophagus in a Teenager: Case Report

Vasile Valeriu Lupu  1 , Ancuta Ignat, Gabriela Paduraru, Doina Mihaila, Marin Burlea, Anamaria Ciubara
Affiliations
Case Reports

Heterotopic Gastric Mucosa in the Distal Part of Esophagus in a Teenager: Case Report

Vasile Valeriu Lupu et al. Medicine (Baltimore). 2015 Oct.

Abstract

Heterotopic gastric mucosa (HGM) of the esophagus is a congenital anomaly consisting of ectopic gastric mucosa. It may be connected with disorders of the upper gastrointestinal tract, exacerbated by Helicobacter pylori. The diagnosis of HGM is confirmed via endoscopy with biopsy. Histopathology provides the definitive diagnosis by demonstrating gastric mucosa adjacent to normal esophageal mucosa. HGM located in the distal esophagus needs differentiation from Barrett's esophagus. Barrett's esophagus is a well-known premalignant injury for adenocarcinoma of the esophagus. Malignant progression of HGM occurs in a stepwise pattern, following the metaplasia-dysplasia-adenocarcinoma sequence.We present a rare case of a teenage girl with HGM located in the distal esophagus, associated with chronic gastritis and biliary duodenogastric reflux. Endoscopy combined with biopsies is a mandatory method in clinical evaluation of metaplastic and nonmetaplastic changes within HGM of the esophagus.

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Conflict of interest statement

The authors have no funding and conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
(A) Gastric heterotopia in the distal part of esophagus; (B) gastric heterotopia in the distal part of esophagus.
FIGURE 2
FIGURE 2
Nodular purpuric gastritis with hypertrophic folds; biliary reflux.
FIGURE 3
FIGURE 3
Histopathologic examination (histopathologic examination [HE] × 100): A—gastric epithelium attached to the esophageal epithelium. B—inflammation and microhemorrhages in the esophageal epithelium. C—inflammation and microhemorrhages in the gastric epithelium.
See this image and copyright information in PMC

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