SnapShot: antiviral restriction factors
- PMID: 26496613
- DOI: 10.1016/j.cell.2015.10.019
SnapShot: antiviral restriction factors
Abstract
Restriction factors are cellular proteins that inhibit viruses at different steps of their replication cycle and represent an important first line of defense against viral pathogens. This SnapShot provides an overview of cell-intrinsic antiviral factors, describes their properties, and illustrates the striking variety of antiviral mechanisms as well the sophisticated viral countermeasures. To view this SnapShot, open or download the PDF.
Copyright © 2015 Elsevier Inc. All rights reserved.
Similar articles
-
Emerging Role of PYHIN Proteins as Antiviral Restriction Factors.Viruses. 2020 Dec 18;12(12):1464. doi: 10.3390/v12121464. Viruses. 2020. PMID: 33353088 Free PMC article. Review.
-
Viral infections and sphingolipids.Handb Exp Pharmacol. 2013;(216):321-40. doi: 10.1007/978-3-7091-1511-4_16. Handb Exp Pharmacol. 2013. PMID: 23563664 Review.
-
Genome guardian p53 and viral infections.Rev Med Virol. 2013 Jul;23(4):213-20. doi: 10.1002/rmv.1738. Epub 2012 Dec 17. Rev Med Virol. 2013. PMID: 23255396 Review.
-
From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections.Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):382-394. doi: 10.1016/j.bbamcr.2018.09.012. Epub 2018 Oct 2. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30290238 Free PMC article. Review.
-
Regulation of Ribosomal Proteins on Viral Infection.Cells. 2019 May 27;8(5):508. doi: 10.3390/cells8050508. Cells. 2019. PMID: 31137833 Free PMC article. Review.
Cited by
-
A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity.J Virol. 2019 Feb 19;93(5):e01432-18. doi: 10.1128/JVI.01432-18. Print 2019 Mar 1. J Virol. 2019. PMID: 30541857 Free PMC article.
-
A novel transposable element-mediated mechanism causes antiviral resistance in Drosophila through truncating the Veneno protein.Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2122026119. doi: 10.1073/pnas.2122026119. Epub 2022 Jul 11. Proc Natl Acad Sci U S A. 2022. PMID: 35858337 Free PMC article.
-
SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation.Cell Rep. 2019 Jul 9;28(2):434-448.e6. doi: 10.1016/j.celrep.2019.06.027. Cell Rep. 2019. PMID: 31291579 Free PMC article.
-
Friends and Foes: The Ambivalent Role of Autophagy in HIV-1 Infection.Viruses. 2024 Mar 25;16(4):500. doi: 10.3390/v16040500. Viruses. 2024. PMID: 38675843 Free PMC article. Review.
-
The Role of Caveolin 1 in HIV Infection and Pathogenesis.Viruses. 2017 May 26;9(6):129. doi: 10.3390/v9060129. Viruses. 2017. PMID: 28587148 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical