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Comment
. 2015 Nov 15;78(10):666-7.
doi: 10.1016/j.biopsych.2015.08.020.

Untangling a role for tau in synucleinopathies

Marion Delenclos  1 , Simon Moussaud  1 , Pamela J McLean  2
Affiliations
Comment

Untangling a role for tau in synucleinopathies

Marion Delenclos et al. Biol Psychiatry. .
No abstract available

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Conflict of interest statement

The authors report no biomedical financial interests or potential conflicts of interest.

Figures

Figure 1
Figure 1
Tau and α-synuclein interactions. Tau and α-synuclein are known to interact at the monomeric level and potentiate each other’s aggregation into homomeric amyloid fibrils. Sengupta et al. demonstrate that under pathologic conditions, tau and α-synuclein also interact to form hybrid co-oligomers that can be recognized by a tau oligomer–specific antibody T22 and the α-synuclein oligomer–specific antibodies F8H7 or syn33.
See this image and copyright information in PMC

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References

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