The Japan Statin Treatment Against Recurrent Stroke (J-STARS) Trial: Where to Now?

Affiliations

Editorial

Graeme J Hankey. EBioMedicine. 2015.

. 2015 Aug 6;2(9):1008-9.

doi: 10.1016/j.ebiom.2015.08.007. eCollection 2015 Sep.

¹ School of Medicine and Pharmacology, The University of Western Australia, Australia.

No abstract available

Comment on

The Japan Statin Treatment Against Recurrent Stroke (J-STARS): A Multicenter, Randomized, Open-label, Parallel-group Study.
Hosomi N, Nagai Y, Kohriyama T, Ohtsuki T, Aoki S, Nezu T, Maruyama H, Sunami N, Yokota C, Kitagawa K, Terayama Y, Takagi M, Ibayashi S, Nakamura M, Origasa H, Fukushima M, Mori E, Minematsu K, Uchiyama S, Shinohara Y, Yamaguchi T, Matsumoto M; J-STARS Collaborators. Hosomi N, et al. EBioMedicine. 2015 Aug 6;2(9):1071-8. doi: 10.1016/j.ebiom.2015.08.006. eCollection 2015 Sep. EBioMedicine. 2015. PMID: 26501105 Free PMC article. Clinical Trial.

1. Cholesterol Treatment Trialists' (CTT) Collaboration Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials. Lancet. 2015;385:1397–1405. - PubMed
1. Cholesterol Treatment Trialists' (CTT) Collaboration Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376:1670–1681. - PMC - PubMed
1. Heart Protection Study Collaborative Group Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet. 2004;363:757–767. - PubMed
1. Hosomi N., Nagai Y., Kohriyama T., Ohtsuki T., Aoki A., Nezu T. The Japan Statin Treatment Against Recurrent Stroke (J-STARS): a multicentre, randomized, open-label, parallel group study. EBioMedicine. 2015;2:1071–1078. - PMC - PubMed
1. Manktelow B.N., Potter J.F. Interventions in the management of serum lipids for preventing stroke recurrence. Cochrane Database Syst. Rev. 2009;3:CD002091. - PubMed