LIVER COMPLICATIONS IN ADULT DENGUE AND CURRENT MANAGEMENT

Abstract

Adult dengue patients have a lower prevalence of bleeding tendency and greater prevalence of abnormal liver function tests than children with dengue infections. At least two-thirds of adult dengue patients have abnormal liver function tests. Our article aims to detail the clinical findings of liver complications in adult patients with dengue infection. The predictors of liver complications and the associations with failure of other organs were reviewed; for example, high-level ALT during the febrile stage has been associated with shock. In addition, this review includes the current interventions for treatment of acute liver failure in adult dengue patients including N-acetylcysteine, and artificial liver dialysis.