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Comment
. 2015 Nov;47(11):1226-7.
doi: 10.1038/ng.3428.

The genomic landscape of adult T cell leukemia/lymphoma

Carmen Vicente  1 , Jan Cools  1
Affiliations
Comment

The genomic landscape of adult T cell leukemia/lymphoma

Carmen Vicente et al. Nat Genet. 2015 Nov.

Abstract

Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large genomic and transcriptomic study of ATL now provides detailed insight into the molecular lesions implicated in the development of this T cell malignancy.

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Comment on

  • Integrated molecular analysis of adult T cell leukemia/lymphoma.
    Kataoka K, Nagata Y, Kitanaka A, Shiraishi Y, Shimamura T, Yasunaga J, Totoki Y, Chiba K, Sato-Otsubo A, Nagae G, Ishii R, Muto S, Kotani S, Watatani Y, Takeda J, Sanada M, Tanaka H, Suzuki H, Sato Y, Shiozawa Y, Yoshizato T, Yoshida K, Makishima H, Iwanaga M, Ma G, Nosaka K, Hishizawa M, Itonaga H, Imaizumi Y, Munakata W, Ogasawara H, Sato T, Sasai K, Muramoto K, Penova M, Kawaguchi T, Nakamura H, Hama N, Shide K, Kubuki Y, Hidaka T, Kameda T, Nakamaki T, Ishiyama K, Miyawaki S, Yoon SS, Tobinai K, Miyazaki Y, Takaori-Kondo A, Matsuda F, Takeuchi K, Nureki O, Aburatani H, Watanabe T, Shibata T, Matsuoka M, Miyano S, Shimoda K, Ogawa S. Kataoka K, et al. Nat Genet. 2015 Nov;47(11):1304-15. doi: 10.1038/ng.3415. Epub 2015 Oct 5. Nat Genet. 2015. PMID: 26437031

References

    1. Semin Hematol. 2015 Apr;52(2):77-85 - PubMed
    1. J Exp Med. 2014 Dec 15;211(13):2497-505 - PubMed
    1. Blood. 2014 Aug 28;124(9):1481-91 - PubMed
    1. Expert Opin Investig Drugs. 2011 Aug;20(8):1167-74 - PubMed
    1. Lancet Oncol. 2014 Oct;15(11):e517-26 - PubMed

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