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. 2015 Oct;78(4):385-9.
doi: 10.4046/trd.2015.78.4.385. Epub 2015 Oct 1.

Single Nodular Pulmonary Amyloidosis: Case Report

Seung Hyun Lee  1 , Young Chun Ko  1 , Jong Pil Jeong  1 , Chan Woo Park  1 , Seok Ho Seo  1 , Jong Taek Kim  1 , Dae Won Park  1 , Cheol Min Bak  1 , Seung Ki Moon  1 , Shin Hyoung Jo  1 , Se Mi Kim  1 , Ah Lon Jung  1
Affiliations

Single Nodular Pulmonary Amyloidosis: Case Report

Seung Hyun Lee et al. Tuberc Respir Dis (Seoul). 2015 Oct.

Abstract

Amyloidosis is defined as the presence of extra-cellular deposits of an insoluble fibrillar protein, amyloid. The pulmonary involvement of amyloidosis is usually classified as tracheobronchial, parenchymal nodular, or diffuse alveolar septal. A single nodular lesion can mimic various conditions, including malignancy, pulmonary tuberculosis, and fungal infection. To date, only one case of nodular pulmonary amyloidosis has been reported in Korea, a case involving multiple nodular lesions. Here, we report and discuss the case of a patient having single nodular amyloidosis.

Keywords: Amyloidosis.

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Conflict of interest statement

Conflicts of Interest: No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1. Simple chest radiography showing a nodular lesion in the right upper lobe inferior margin near the hilum.
Figure 2
Figure 2. (A, B) Chest computed tomography showing an approximately 1.8-cm subpleural nodular consolidation with some spiculation in the inferior margin of the right upper lobe (arrowheads).
Figure 3
Figure 3. Histopathological examination of the nodule showing eosinophilic, amorphous material deposits (H&E stain, ×100).
Figure 4
Figure 4. The nodule shows an apple-green birefringence, that is regarded as diagnostic (Congo red staining, as seen under a polarized microscope, ×100).
Figure 5
Figure 5. Normal serum protein electrophoresis (EP) results. SPE: serum protein electrophoresis.
See this image and copyright information in PMC

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