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Case Reports
. 2015 Oct;3(10):888-90.
doi: 10.1002/ccr3.325. Epub 2015 Sep 10.

Sclerosing angiomatoid nodular transformation of the spleen

Vidhya Murthy  1 , Ben Miller  1 , Emmanuel M Nikolousis  1 , Guy Pratt  1 , Zbigniew Rudzki  1
Affiliations
Case Reports

Sclerosing angiomatoid nodular transformation of the spleen

Vidhya Murthy et al. Clin Case Rep. 2015 Oct.

Abstract

Sclerosing angiomatoid nodular transformation (SANT) of spleen is a very rare benign entity with unknown etiology. Here, we report this unusual case in a fit middle-aged gentleman and discuss various diagnostic modalities along with the management of this condition.

Keywords: Incidental splenic mass; splenectomy; splenic biopsy; spokes wheel pattern.

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Figures

Figure 1
Figure 1
Computed tomography (CT).
Figure 2
Figure 2
Spleen Macro.
Figure 3
Figure 3
Spleen H+E.
Figure 4
Figure 4
CD8 immunostain.
Figure 5
Figure 5
CD31 Immunostain.
Figure 6
Figure 6
Cd34 immunostain.
See this image and copyright information in PMC

References

    1. Martel M, Cheuk W, Lombardi L, Lifschitz-Mercer B, Chan JK. Rosai J. Sclerosing angiomatoid nodular transformation (SANT): report of 25 cases of distinctive benign splenic lesion. Am. J. Surg. Pathology. 2004;28:1268–1279. - PubMed
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    1. Devrim A, et al. CT and MRI findings of sclerosing angiomatoid nodular transformation of the spleen: spoke wheel pattern. Korean J. Radiol. 2008;99(Suppl):S52–S55. - PMC - PubMed
    1. Feng YM, Huang YC, TU CW, Kao WS. Tu DG. Distinctive PET/CT features of splenic SANT. Clin. Nucl. Med. 2013;38:e465–e466. - PubMed

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