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. 2015 Oct 28:15:141.
doi: 10.1186/s12877-015-0140-y.

The effect of early surgery after hip fracture on 1-year mortality

Paola Colais  1 , Mirko Di Martino  2 , Danilo Fusco  3 , Carlo Alberto Perucci  4 , Marina Davoli  5
Affiliations

The effect of early surgery after hip fracture on 1-year mortality

Paola Colais et al. BMC Geriatr. .

Abstract

Background: Hip fracture injuries are identified as one of the most serious healthcare problems affecting older people. Many studies have explored the associations among patient characteristics, treatment processes, time to surgery and various outcomes in patients hospitalized for hip fracture. The objective of the present study is to evaluate the difference in 1-year mortality after hip fracture between patients undergoing early surgery (within 2 days) and patients undergoing delayed surgery in Italy.

Methods: Observational, retrospective study based on the Hospital Information System (HIS). This cohort study included patients aged 65 years and older who were residing in Italy and were admitted to an acute care hospital for a hip fracture between 1 January 2007 and 31 December 2012. A multivariate Cox regression analysis was used to assess the effect of early surgery on the likelihood of 1-year mortality after hip fracture, adjusting for risk factors that could affect the outcome under study. The absolute number of deaths prevented by exposure to early surgery was calculated.

Results: We studied a total of 405,037 admissions for hip fracture. Patients who underwent surgery within 2 days had lower 1-year mortality compared to those who waited for surgery more than 2 days (Hazard Ratios -HR-: 0.83; 95 % CI: 0.82-0.85). The number of deaths prevented by the exposure to early surgery was 5691.

Conclusions: This study is the first to evaluate the association between time to surgery and 1-year mortality for all Italian elderly patients hospitalized for hip fracture. The study confirmed the previous reports on the association between delayed surgery and increased mortality and complication rates in elderly patients admitted for hip fracture. Our data support the notion that deviating from surgical guidelines in hip fracture is costly, in terms of both human life and excess hospital stay.

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Figures

Fig. 1
Fig. 1
Number of hip fractures and 1-year crude mortality by year and time to surgery
Fig. 2
Fig. 2
Adjusted hazard functions of 1-year mortality by time to surgery
Fig. 3
Fig. 3
Number of deaths prevented by exposure to early intervention by year
Fig. 4
Fig. 4
The time-dependent effects of early surgery on mortality by age group
See this image and copyright information in PMC

References

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