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. 2016 Jan;54(1):197-9.
doi: 10.1128/JCM.02093-15. Epub 2015 Oct 28.

Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia

M Hussein Gasem  1 , Helmia Farida  2 , Ahmed Ahmed  3 , Juliţte A Severin  4 , Agus Suryanto  5 , Bambang Isbandrio  6 , Henri A Verbrugh  4 , Rudy A Hartskeerl  3 , Peterhans J van den Broek  7
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Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia

M Hussein Gasem et al. J Clin Microbiol. 2016 Jan.

Abstract

We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acute-phase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis.

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