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Review
. 2016;9(1):27-34.
doi: 10.1586/17512433.2016.1100072. Epub 2015 Oct 29.

Bupropion-SR plus naltrexone-SR for the treatment of mild-to-moderate obesity

Khawla F Ali  1 , Alpana P Shukla  1 , Louis J Aronne  1
Affiliations
Review

Bupropion-SR plus naltrexone-SR for the treatment of mild-to-moderate obesity

Khawla F Ali et al. Expert Rev Clin Pharmacol. 2016.

Abstract

Naltrexone-bupropion is a recently approved drug combination for chronic weight management. In this article, we discuss the rationale for its use as a combination followed by a comprehensive review of safety and efficacy data from major preclinical, phase II and III clinical trials.

Keywords: Naltrexone; bupropion; obesity; type 2 diabetes; weight loss.

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