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Editorial
. 2015;14(23):3665-6.
doi: 10.1080/15384101.2015.1112614.

GIP/MZT1 proteins: Key players in centromere regulation

Anne-Catherine Schmit  1 , Etienne Herzog  1 , Marie-Edith Chabouté  1
Affiliations
Editorial

GIP/MZT1 proteins: Key players in centromere regulation

Anne-Catherine Schmit et al. Cell Cycle. 2015.
No abstract available

Keywords: CENH3 loading and maintenance; GIP/MZT1; centromeric cohesion; nuclear envelope.

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Figures

Figure 1.
Figure 1.
GIP/MZT1 proteins coordinate centromere functions and the establishment of the microtubule (MT) network at the nuclear envelope. GIPs are regulatory proteins, specific of gamma-tubulin complexes at the outer nuclear membrane and of centromeric complexes close to the inner nuclear membrane. At the centromere, they contribute to CENH3 loading and maintenance and ensure centromeric cohesion.
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Comment on

  • Comment on: Batzenschlager M, et al. Arabidopsis MZT1 homologs GIP1 and GIP2 are essential for centromere architecture. Proc Natl Acad Sci U S A 2015; 112(28):8656–60; PMID: 26124146; http://dx.doi.org/10.1073/pnas.1506351112. doi: 10.1073/pnas.1506351112

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