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Review
. 2015 Dec;15(12):119.
doi: 10.1007/s11892-015-0692-4.

Challenges and Opportunities in the Management of Cardiovascular Risk Factors in Youth With Type 1 Diabetes: Lifestyle and Beyond

Michelle Katz  1 , Elisa Giani  2 , Lori Laffel  3
Affiliations
Review

Challenges and Opportunities in the Management of Cardiovascular Risk Factors in Youth With Type 1 Diabetes: Lifestyle and Beyond

Michelle Katz et al. Curr Diab Rep. 2015 Dec.

Abstract

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in persons with type 1 diabetes (T1D). Specific risk factors associated with diabetes, such as hyperglycemia and kidney disease, have been demonstrated to increase the incidence and progression of CVD. Nevertheless, few data exist on the effects of traditional risk factors such as dyslipidemia, obesity, and hypertension on CVD risk in youth with T1D. Improvements in understanding and approaches to the evaluation and management of CVD risk factors, specifically for young persons with T1D, are desirable. Recent advances in noninvasive techniques to detect early vascular damage, such as the evaluation of endothelial dysfunction and aortic or carotid intima-media thickness, provide new tools to evaluate the progression of CVD in childhood. In the present review, current CVD risk factor management, challenges, and potential therapeutic interventions in youth with T1D are described.

Keywords: Cardiovascular; Diabetes type 1; Lifestyle; Pediatrics.

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Conflict of interest statement

Conflict of Interest

Michelle Katz and Elisa Giani declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Flow-chart of risk factors and opportunities in the management of cardiovascular risk factors in type 1 diabetes.
See this image and copyright information in PMC

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