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. 2015 Dec;34(12):1495-504.
doi: 10.1016/j.healun.2015.10.003. Epub 2015 Oct 8.

Seventh INTERMACS annual report: 15,000 patients and counting

James K Kirklin  1 , David C Naftel  2 , Francis D Pagani  3 , Robert L Kormos  4 , Lynne W Stevenson  5 , Elizabeth D Blume  6 , Susan L Myers  2 , Marissa A Miller  7 , J Timothy Baldwin  7 , James B Young  8
Affiliations

Seventh INTERMACS annual report: 15,000 patients and counting

James K Kirklin et al. J Heart Lung Transplant. 2015 Dec.

Abstract

The seventh annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes the first 9 years of patient enrollment. The Registry includes >15,000 patients from 158 participating hospitals. Trends in device strategy, patient profile at implant and survival are presented. Risk factors for mortality with continuous-flow pumps are updated, and the major causes/modes of death are presented. The adverse event burden is compared between eras, and health-related quality of life is reviewed. A detailed analysis of outcomes after mechanical circulatory support for ambulatory heart failure is presented. Recent summary data from PediMACS and MedaMACS is included. With the current continuous-flow devices, survival at 1 and 2 years is 80% and 70%, respectively.

Keywords: INTERMACS; advanced heart failure; destination therapy; mechanical support; ventricular assist device.

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