Clinical Trial
doi: 10.1016/0167-8140(89)90165-5.
Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer
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- PMID: 2652199
- DOI: 10.1016/0167-8140(89)90165-5
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Clinical Trial
Ten-year results of a randomized trial comparing a conservative treatment to mastectomy in early breast cancer
Radiother Oncol.
1989 Mar.
Abstract
A randomized trial was conducted at the Institut Gustave-Roussy (IGR) between 1972 and 1980 comparing tumorectomy and breast irradiation with modified radical mastectomy. One hundred and seventy-nine patients with an infiltrating breast carcinoma up to 20 mm in diameter at macroscopic examination were included: 88 had conservative management, and 91 a mastectomy. All patients had a low-axillary dissection with immediate histological examination. For the patients with positive axillary nodes, a complete axillary dissection was undertaken. Overall survival, distant metastasis, contralateral breast cancer and locoregional recurrence rates were not significantly different between the two treatment groups.
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