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Review
. 2015 Sep;21(3):200-11.
doi: 10.3350/cmh.2015.21.3.200. Epub 2015 Sep 30.

Personalized management of cirrhosis by non-invasive tests of liver fibrosis

Grace Lai-Hung Wong  1 , Wendell Zaragoza Espinosa  2 , Vicnent Wai-Sun Wong  1
Affiliations
Review

Personalized management of cirrhosis by non-invasive tests of liver fibrosis

Grace Lai-Hung Wong et al. Clin Mol Hepatol. 2015 Sep.

Abstract

Owing to the high prevalence of various chronic liver diseases, cirrhosis is one of the leading causes of morbidity and mortality worldwide. In recent years, the development of non-invasive tests of fibrosis allows accurate diagnosis of cirrhosis and reduces the need for liver biopsy. In this review, we discuss the application of these non-invasive tests beyond the diagnosis of cirrhosis. In particular, their role in the selection of patients for hepatocellular carcinoma surveillance and varices screening is highlighted.

Keywords: FibroScan; FibroTest; Hepatocellular carcinoma; Transient elastography; Varices.

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Conflict of interest statement

Conflicts of Interest: Grace Wong has served as an advisory board member for Gilead and received paid lecture fees from AbbVie, Bristol-Myers Squibb, Echosens, Gilead and Janssen. Vincent Wong has served as an advisory board member for Gilead and Janssen and a consultant for AbbVie, Merck and NovoMedica, and received paid lecture fees from AbbVie, Echosens and Gilead.

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