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Review
. 2016 Jan;73(1):13-4.
doi: 10.1001/jamaneurol.2015.2960.

Blood-Brain Barrier Permeability and Gadolinium: Benefits and Potential Pitfalls in Research

Axel Montagne  1 , Arthur W Toga  2 , Berislav V Zlokovic  1
Affiliations
Review

Blood-Brain Barrier Permeability and Gadolinium: Benefits and Potential Pitfalls in Research

Axel Montagne et al. JAMA Neurol. 2016 Jan.
No abstract available

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Conflict of interest statement

Conflict of interest disclosure

None of the authors has conflict of interest.

References

    1. Zlokovic BV. Neurovascular pathways to neurodegeneration in Alzheimer’s disease and other disorders. Nat Rev Neurosci. 2011;12(12):723–738. - PMC - PubMed
    1. Kanal E, Tweedle MF. Residual or retained gadolinium: practical implications for radiologists and our patients. Radiology. 2015;275(3):630–634. - PubMed
    1. Montagne A, Barnes SR, Sweeney MD, et al. Blood-brain barrier breakdown in the aging human hippocampus. Neuron. 2015;85(2):296–302. - PMC - PubMed
    1. Kanda T, Ishii K, Kawaguchi H, et al. High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology. 2014;270(3):834–841. - PubMed
    1. McDonald RJ, McDonald JS, Kallmes DF, et al. Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology. 2015;275(3):772–782. - PubMed

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