Synthesis at the Speed of Codons
- PMID: 26526516
- DOI: 10.1016/j.tibs.2015.10.005
Synthesis at the Speed of Codons
Abstract
The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.
Copyright © 2015. Published by Elsevier Ltd.
Comment on
-
Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding.Mol Cell. 2015 Sep 3;59(5):744-54. doi: 10.1016/j.molcel.2015.07.018. Epub 2015 Aug 27. Mol Cell. 2015. PMID: 26321254 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
