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Comment
. 2015 Dec;40(12):717-718.
doi: 10.1016/j.tibs.2015.10.005. Epub 2015 Oct 31.

Synthesis at the Speed of Codons

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Synthesis at the Speed of Codons

Kristin S Koutmou et al. Trends Biochem Sci. 2015 Dec.

Abstract

The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.

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