Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016:67:215-28.
doi: 10.1146/annurev-med-011514-023043. Epub 2015 Nov 2.

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure

Alyssa R Martin  1 , Robert F Siliciano  2   3
Affiliations
Review

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure

Alyssa R Martin et al. Annu Rev Med. 2016.

Abstract

An estimated 35 million people worldwide are infected with HIV, yet a widely applicable cure strategy remains elusive. Recent case reports have suggested that curing HIV infection is possible, renewing excitement about research efforts. We describe those cases and discuss their relevance to the global HIV epidemic. We also review ongoing cure strategies that are transitioning from the lab to the clinic, and the assays and clinical assessments that can be used to evaluate cure interventions.

Keywords: HIV-1; early treatment; genome editing; persistence; shock and kill; vaccine.

PubMed Disclaimer

Publication types

LinkOut - more resources