Comment on

• Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.

  Fuchikami M, Thomas A, Liu R, Wohleb ES, Land BB, DiLeone RJ, Aghajanian GK, Duman RS. Fuchikami M, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8106-11. doi: 10.1073/pnas.1414728112. Epub 2015 Jun 8. Proc Natl Acad Sci U S A. 2015. PMID: 26056286 Free PMC article.
• Activation of AMPA Receptors Mediates the Antidepressant Action of Deep Brain Stimulation of the Infralimbic Prefrontal Cortex.

  Jiménez-Sánchez L, Castañé A, Pérez-Caballero L, Grifoll-Escoda M, López-Gil X, Campa L, Galofré M, Berrocoso E, Adell A. Jiménez-Sánchez L, et al. Cereb Cortex. 2016 Jun;26(6):2778-2789. doi: 10.1093/cercor/bhv133. Epub 2015 Jun 17. Cereb Cortex. 2016. PMID: 26088969