Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Nov;4(6):553-67.
doi: 10.2217/cer.15.42. Epub 2015 Nov 4.

Screening for breast cancer with Breast-CT in a ProHTA simulation

Georg Ruile  1   2 , Anatoli Djanatliev  3 , Christine Kriza  2   4 , Florian Meier  5 , Ines Leb  6 , Willi A Kalender  1   2 , Peter L Kolominsky-Rabas  2   4 ; National Leading-Edge Cluster Medical Technologies ‘Medical Valley EMN’
Affiliations
Free article

Screening for breast cancer with Breast-CT in a ProHTA simulation

Georg Ruile et al. J Comp Eff Res. 2015 Nov.
Free article

Abstract

Aims: The potential of dedicated Breast-CT is evaluated by simulating its impact onto the performance of the German breast cancer screening program. Attendance rates, cancer detection and economic implications are quantified.

Methods: Based on a prospective health technology assessment approach, we simulated screening in different scenarios.

Results: In the simulation, attendance rates increase from 54 to up to 72% due to reduced pain. Breast cancers will be detected earlier while nodal positives and distant recurrences decrease. Assuming no additional cost, cost savings of up to €55 million in one screening period are computed.

Conclusion: The simulation indicates that earlier cancer detection, fewer unnecessary biopsies and less pain are potential benefits of Breast-CT resulting in cost savings and higher attendance.

Keywords: breast cancer; computed tomography; health economics; health technology assessment; mammography screening; simulation.

PubMed Disclaimer

Publication types