Looking into the Black Box of Synaptic Vesicle Recruitment
- PMID: 26539883
- DOI: 10.1016/j.neuron.2015.10.028
Looking into the Black Box of Synaptic Vesicle Recruitment
Abstract
To sustain ongoing synaptic transmission, new transmitter-filled vesicles must be recruited to empty release sites rapidly. However, in this issue of Neuron, Midorikawa and Sakaba (2015) show that, before being released, vesicles are tethered at the membrane for seconds.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Imaging Exocytosis of Single Synaptic Vesicles at a Fast CNS Presynaptic Terminal.Neuron. 2015 Nov 4;88(3):492-8. doi: 10.1016/j.neuron.2015.09.047. Neuron. 2015. PMID: 26539890