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Comment
. 2015 Nov 4;88(3):435-7.
doi: 10.1016/j.neuron.2015.10.028.

Looking into the Black Box of Synaptic Vesicle Recruitment

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Comment

Looking into the Black Box of Synaptic Vesicle Recruitment

Stefan Hallermann. Neuron. .

Abstract

To sustain ongoing synaptic transmission, new transmitter-filled vesicles must be recruited to empty release sites rapidly. However, in this issue of Neuron, Midorikawa and Sakaba (2015) show that, before being released, vesicles are tethered at the membrane for seconds.

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