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. 2015 Sep-Oct;48(5):305-13.
doi: 10.1590/0100-3984.2014.0084.

Optimization of OSEM parameters in myocardial perfusion imaging reconstruction as a function of body mass index: a clinical approach

Pietro Paolo de Barros  1 , Luis F Metello  2 , Tatiane Sabriela Cagol Camozzato  3 , Domingos Manuel da Silva Vieira  4
Affiliations

Optimization of OSEM parameters in myocardial perfusion imaging reconstruction as a function of body mass index: a clinical approach

Pietro Paolo de Barros et al. Radiol Bras. 2015 Sep-Oct.

Abstract
in English, Portuguese

Objective: The present study is aimed at contributing to identify the most appropriate OSEM parameters to generate myocardial perfusion imaging reconstructions with the best diagnostic quality, correlating them with patients' body mass index.

Materials and methods: The present study included 28 adult patients submitted to myocardial perfusion imaging in a public hospital. The OSEM method was utilized in the images reconstruction with six different combinations of iterations and subsets numbers. The images were analyzed by nuclear cardiology specialists taking their diagnostic value into consideration and indicating the most appropriate images in terms of diagnostic quality.

Results: An overall scoring analysis demonstrated that the combination of four iterations and four subsets has generated the most appropriate images in terms of diagnostic quality for all the classes of body mass index; however, the role played by the combination of six iterations and four subsets is highlighted in relation to the higher body mass index classes.

Conclusion: The use of optimized parameters seems to play a relevant role in the generation of images with better diagnostic quality, ensuring the diagnosis and consequential appropriate and effective treatment for the patient.

Objetivo: O presente trabalho visa contribuir para identificar quais os parâmetros OSEM que geram as reconstruções na cintilografia de perfusão do miocárdio com o maior valor clínico de diagnóstico, relacionando-os com as classificações de índice de massa corporal.

Materiais e métodos: Foram selecionados 28 pacientes adultos que realizaram cintilografia de perfusão do miocárdio em um hospital público. Cada paciente teve seu exame processado com o método OSEM em seis combinações diferentes de número de iterações e subsets. As imagens foram analisadas por especialistas em cardiologia nuclear, que consideraram o valor clínico de diagnóstico delas e indicaram quais as imagens que mais se adequavam à qualidade diagnóstica.

Resultados: Em análise global da pontuação conforme as avaliações médicas, o arranjo de quatro iterações e quatro subsets gerou as imagens com melhor qualidade diagnóstica em todas as classes de índice de massa corporal, porém o arranjo com seis iterações e quatro subsets se destacou nas classes de maiores índices de massa corporal.

Conclusão: A utilização de parâmetros otimizados parece ter papel importante em proporcionar reconstruções de melhor qualidade diagnóstica, garantindo-se assim que o paciente tenha o seu diagnóstico e consequente terapêutica encaminhados de forma mais adequada e eficaz.

Keywords: Image reconstruction; Iterative methods; Myocardial perfusion imaging; Nuclear cardiology; Nuclear medicine.

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Figures

Figure 1
Figure 1
Defined combinations of iterations and subsets numbers for the study.
Figure 2
Figure 2
Display of reconstructed images on the A3 size sheet.
Figure 3
Figure 3
Axial short axis, vertical long axis and horizontal long axis resulted from image processing.
Figure 4
Figure 4
General chart showing the parameters selected as a first option by the specialists.
Figure 5
Figure 5
Resulting images from processing using four iterations and four subsets.
See this image and copyright information in PMC

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