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. 2015:2015:742658.
doi: 10.1155/2015/742658. Epub 2015 Oct 12.

Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging

Tarek M Mousa  1 , Oluwaseun A Akinseye  2 , Ketevan Berekashvili  3 , Olakunle O Akinboboye  1
Affiliations

Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging

Tarek M Mousa et al. Int J Hypertens. 2015.

Abstract

Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and central BP measurements were completed at first visit and at 4 weeks in 65 healthy volunteers who were at least 40 years old and not on medication. Subjects were divided into two groups of normotensives and prehypertensives based on JNC-7 criteria and LVM was obtained using cardiac magnetic resonance imaging. Prehypertensives had significantly higher LVMI compared to normotensives (P < 0.01). Brachial and central BP also both positively correlate with LVMI (r = 0.460, P < 0.01; r = 0.318, P = 0.012, resp.) in both groups and neither method was superior to the other. After multivariate regression analysis and adjusting for cardiovascular risk factors, prehypertension remained an independent determinant of LVM. Conclusion. Prehypertension is associated with cardiovascular target organ damage, and central BP was not superior to brachial BP or vice versa for association with LVMI.

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Figures

Figure 1
Figure 1
LV mass index in prehypertensive versus normotensive volunteers.
Figure 2
Figure 2
Brachial and central diastolic blood pressure measurements.
Figure 3
Figure 3
Brachial and central systolic blood pressure measurements.
Figure 4
Figure 4
Correlation between LV mass index (kg/m2) and brachial systolic blood pressure.
Figure 5
Figure 5
Correlation between LV mass index (kg/m2) and central systolic blood pressure.
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