Update on Disease-Modifying/Preventive Therapies in Alzheimer's Disease

Abstract

Alzheimer's disease (AD) is increasingly becoming a major health problem throughout the US and Western Europe. As the remnants of the Baby Boom generation begin to reach their seniority at the turn of the twenty-first century, the disease has been unwillingly brought to the attention of the public eye. A disease that has traditionally been associated with an aging population has thus become a heated topic of discussion as modern research attempts to prevent and treat this major health burden and plague of the next decade.

Keywords: Alzheimer’s disease (AD); Amyloid Aβ; Amyloid plaques; Cognition; Early-onset Alzheimer’s disease; Late-onset Alzheimer’s disease; Medical illness; Mild AD; Mild cognitive impairment (MCI); Prodromal AD; Tau protein; ε4 allele.